产品货号：
Z36517
中文名称：
RAB13抗体
英文名称：
Anti-RAB13 Antibody (Clone#1600CT845.37.29)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RAB13 Antibody (Clone#1600CT845.37.29) |
| 指标别名 | RAB13;GIG4;Ras-related protein Rab-13;Cell growth-inhibiting gene 4 protein |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | RAB13 |
| 克隆号 | 1600CT845.37.29 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | This RAB13 antibody is generated from a mouse immunized with a recombinant protein between 1-203 amino acids from human RAB13. |
| 计算分子量 | 23kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | The small GTPases Rab are key regulators of intracellular membrane trafficking,from the formation of transport vesicles to their fusion with membranes.Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation,movement,tethering and fusion.That Rab is involved in endocytic recycling and regulates the transport to the plasma membrane of transmembrane proteins like the tight junction protein OCLN/occludin.Thereby,it regulates the assembly and the activity of tight junctions.Moreover,it may also regulate tight junction assembly by activating the PKA signaling pathway and by reorganizing the actin cytoskeleton through the activation of the downstream effectors PRKACA and MICALL2 respectively.Through its role in tight junction assembly,may play a role in the establishment of Sertoli cell barrier.Plays also a role in angiogenesis through regulation of endothelial cells chemotaxis.Also involved in neurite outgrowth.Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome.Finally,it has been involved in insulin- induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore may play a role in glucose homeostasis. |
| Uniprot ID | P51153 |
相关搜索：RAB13抗体，RAB13单抗，Anti-RAB13 Antibody (Clone#1600CT845.37.29)